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Radiotracers for NIS imaging studies

March 3, 2017

There are a lot of reasons to love the nuclear reporter NIS: it is non-immunogenic, gives beautiful high resolution 3D images, works for deep tissue and large animal imaging, is fully quantitative, and is translatable to the clinic. It’s an impressive list; maybe impressive enough that you want to try NIS imaging. But now what do you do? How do you get started?

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Which antibiotic selection gene?

February 8, 2017

Imanis Life Sciences | Rochester MN I grow a lot of reporter cell lines, and most of them are under antibiotic selection. Sure, it takes me more time to prepare culture media, but the tradeoff is that I have populations of high reporter-expressing cells that were a lot less work to make than if I […]

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Problems with immunogenic reporter genes

January 25, 2017

Imanis Life Sciences | Rochester MN It seems like there’s a lot of confusion about the immunogenicity of tumor models expressing reporter genes. In fact, the question I may get asked the most here at Imanis is probably whether our murine cell lines will grow in syngeneic immunocompetent mice. It doesn’t seem like a hard […]

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What people say about Imanis

Our group has, and continues to, use NIS as a noninvasive reporter for cell transplantation studies in mice and in pigs. Imanis has provided expert technical and analytical support for this research, and has allowed us to publish our research in high impact journals, including Science Translational Medicine..

– Dr. Raymond Hickey, Mayo Clinic

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