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Measles-CEA

  • 1.0 mL / Purified (OV1004) $ 2,250

Ready to use oncolytic MV-CEA virus

  • Description: Live attenuated Edmonston strain measles virus encoding the secreted human carcinoembryonic antigen (MV-CEA)
  • Strain: Edmonston vaccine lineage
  • Transgene: Secreted human carcinoembryonic antigen, inserted upstream of the nucleocapsid (N) gene
  • Biosafety Level: 1
  • Reference: Peng et al. Nat Med, 2002 May;8(5):527-31.
  • Titer: Purified (purified supernatant, >1e7 TCID50/ml)
  • Propagation method: Inoculate producer cell (e.g. Vero) at MOI of 0.02 for 2-3 hours. Harvest cells when 80-90% of cell monolayer has formed syncytia. Freeze/thaw 2 cycles and freeze aliquots.
  • Proposed Use: Ready to use for generation of new viral stocks and in cell killing assays
  • USDA permit required for shipping? No.

Use Fewer Animals

Our Reduction Campaign

At Imanis, we are committed to promoting the practice of the 3Rs in animal research. Learn how we are decreasing the use of animals and research as well as saving up to 15% on your orders. Continue reading...

Use Fewer Animals

Our Reduction Campaign

At Imanis, we are committed to promoting the practice of the 3Rs in animal research. Learn how we are decreasing the use of animals and research as well as saving up to 15% on your orders. Continue reading...